Advances in Membrane Proteins: Building, Signaling and Malfunction

This book reviews recent advances regarding membrane proteins’ biochemical and biophysical properties and their applications in biomedicine. Divided into two thematic parts, this second volume addresses proteins’ formation, signaling, and malfunctions. It covers several essential membrane proteins, including receptors, cell adhesion molecules, single-transmembrane proteins, and viral membrane proteins. It discusses their structures, functions, related diseases, and roles in drug discovery in detail.

In turn, the book elucidates the lifecycle of membrane proteins, including their synthesis and facilitated folding process, and QC procedures for their production. Additional topics include fundamental concepts, the latest findings, and critical puzzles yet to be solved. Given its scope, the book will appeal to a broad readership in membrane structural and functional biology. Junior scientists can use it as an introduction to the field, while advanced scientists will find a wider view of the field beyond their area of specialization.